Original Article

Roles of Biopsychosocial Factors in the Development of Breast Cancer


  • Mine Özkan
  • Nazmiye Yıldırım
  • Rian Dişçi
  • Ahmet Serkan İlgün
  • Dauren Sarsenov
  • Gül Alço
  • Fatma Aktepe
  • Nesiba Kalyoncu
  • Filiz İzci
  • Derya Selamoğlu
  • Çetin Ordu
  • Kezban Nur Pilancı
  • Zeynep İyigün Erdoğan
  • Yeşim Eralp
  • Vahit Özmen

Received Date: 24.03.2017 Accepted Date: 07.08.2017 Eur J Breast Health 2017;13(4):206-212


The aim of this study was to determine the roles of biopsychosocial risk factors in the development of breast cancer.

Materials and methods:

This hospital-based case-control study included 491 women with breast cancer (study group) and 512 women who did not have cancer or other serious diseases (control group). Biological, psychological, and social risk factors were compared between the two groups. Data were collected using the semi-structured interview, the Stress Assessment Form, and the Coping Strategy Indicator to assess these factors.


When the significantly different biopsychosocial variables between the study and the control groups were evaluated together, independent breast cancer risk factors were found as follows: a stressor experienced in the last 5 years, age 40 years and older, inadequate social support perception, use of avoidance coping strategy, being a housewife, having a family history of cancer, and having a body mass index ≥25.


This study showed a relationship between breast cancer risk and manageable variables (obesity, stressor and coping strategy, social support, and employment status), age and family history of cancer, which are biopsychosocial factors. Biopsychosocial aspects are becoming a greater part of many different healthcare systems.

Keywords: Breast cancer, coping, psychosocial stress, risk factors, social support